The choice to keep POJOs pure doesn't come without cost. Rather than spending the effort to develop and maintain complex configuration files it is possible to simply use annotations to mark classes and let spring do the rest of the work. Resolving dependencies can be simple if they follow a convention such as matching by type or by name. This is choosing convention over configuration .  It is also arguable that, when refactoring to another framework, removing framework specific annotations would be a trivial part of the task  and many injection annotations are now standardized.  
It is possible to safely and accurately administer your injectable medications in the privacy of your home. Safe injection practices protect the patient, the person giving the injection, as well as the environment. The two common types of injections administered at home are subcutaneous, which includes the administration of insulin, and intramuscular injections. If you must give yourself injections or give injections to a close friend or family member, you must first learn how to do so from the healthcare provider who is prescribing the medication to be injected.
“They didn’t cut out the stuff that’s expensive, or the stuff that’s hard to do, or the stuff that makes the place look bad,” said Gastfriend, who has consulted with several states, cities, and foreign countries on addiction issues. He called the report a model for other cities, saying that the task force “seemed to want something that was scientifically valid, meaningful, a true guide to things needed for dealing with this epidemic.” He was impressed that the report not only seeks to expand use of medication-assisted treatments like buprenorphine but seeks to track how many get it.