Corticosteroids uses

There is no evidence of safe and effective use of topical corticosteroids in pregnant mothers. Therefore, they should be used only if clearly needed. Long term use and large applications of topical corticosteroids may cause birth defects in the unborn. It is not known whether topical corticosteroids enter breast milk. Therefore, caution must be exercised before using it in nursing mothers. Topical corticosteroids should not be applied to the breasts of nursing mothers unless the mothers instructed to do so by the physician.

Because of these side effects, doctors frequently choose safer medications, such as the 5-ASA drugs and antibiotics, as initial therapy. But there are a number of ways to reduce the risk of developing side effects. These include rapid but careful tapering off of steroids; alternate-day dosing; rectally applied corticosteroids; and rapidly metabolized corticosteroids such as budesonide (described above). To help prevent osteoporosis, many doctors routinely prescribe calcium supplements as well as multivitamins that contain vitamin D. Another option is the use of bisphosphonates, such as risedronate (Actonel®) and alendronate (Fosamax®). These compounds, which have been shown to help avert bone loss, are effective in treating and preventing steroid-induced osteoporosis.

Corticosteroids may play a useful role in cancer treatment. Since they are strongly anti-inflammatory they are sometimes prescribed to reduce swelling and pain. They may be used with other drugs to reduce nausea and vomiting created by chemotherapy treatment. They may also increase appetite. In a few types of cancer, specific corticosteroids are sometimes used with or without chemotherapy drugs to destroy cancer cells. It's important to note that while corticosteroids can be an important aspect of treatment in some types of cancer, they may not be helpful in all types.

Studies on corticosteroids tend to lean toward the extreme use, rather than the average use.  For example, some studies look at corticosteroids for extreme and rarer cases of eczema.  This makes it harder to research what long-term studies are out there on steroid use.  To complicate things further, corticosteroids can be oral, topical, injected, or inhaled, and this dramatically changes the benefits and risks, and in turn the short-term and long-term effects.  Speak with your doctor and pharmacist on what, if any, long-term studies out there are relevant to your own medical treatment.

Corticosteroids uses

corticosteroids uses

Studies on corticosteroids tend to lean toward the extreme use, rather than the average use.  For example, some studies look at corticosteroids for extreme and rarer cases of eczema.  This makes it harder to research what long-term studies are out there on steroid use.  To complicate things further, corticosteroids can be oral, topical, injected, or inhaled, and this dramatically changes the benefits and risks, and in turn the short-term and long-term effects.  Speak with your doctor and pharmacist on what, if any, long-term studies out there are relevant to your own medical treatment.

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